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Zscan4 binds nucleosomal microsatellite DNA and protects mouse two-cell embryos from DNA damage
Zinc finger protein Zscan4 is selectively expressed in mouse two-cell (2C) embryos undergoing zygotic genome activation (ZGA) and in a rare subpopulation of embryonic stem cells with 2C-like features. Here, we show that Zscan4 specifically recognizes a subset of (CA)(n) microsatellites, repeat seque...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7083622/ https://ncbi.nlm.nih.gov/pubmed/32219172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz9115 |
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