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Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation

Recent work suggests extensive adaptation of transposable elements (TEs) for host gene regulation. However, high numbers of integrations typical of TEs, coupled with sequence divergence within families, have made systematic interrogation of the regulatory contributions of TEs challenging. Here, we e...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fuentes, Daniel R, Swigut, Tomek, Wysocka, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158008/
https://ncbi.nlm.nih.gov/pubmed/30070637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35989
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