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Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation

Recent work suggests extensive adaptation of transposable elements (TEs) for host gene regulation. However, high numbers of integrations typical of TEs, coupled with sequence divergence within families, have made systematic interrogation of the regulatory contributions of TEs challenging. Here, we e...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Fuentes, Daniel R, Swigut, Tomek, Wysocka, Joanna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158008/
https://ncbi.nlm.nih.gov/pubmed/30070637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35989
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