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BTK Inhibitors: present and future

Bruton tyrosine kinase (BTK) is a nonreceptor tyrosine kinase which plays a central role in the signal transduction of the B cell antigen receptor (BCR) and other cell surface receptors, both in normal and malignant B lymphocytes. BCR signaling is activated in secondary lymphatic organs and drives t...

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Bibliographic Details
Published in:Cancer J
Main Author: Burger, Jan A
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083517/
https://ncbi.nlm.nih.gov/pubmed/31764119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000412
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