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BTK Inhibitors: present and future

Bruton tyrosine kinase (BTK) is a nonreceptor tyrosine kinase which plays a central role in the signal transduction of the B cell antigen receptor (BCR) and other cell surface receptors, both in normal and malignant B lymphocytes. BCR signaling is activated in secondary lymphatic organs and drives t...

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Detalles Bibliográficos
Publicado en:Cancer J
Autor principal: Burger, Jan A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083517/
https://ncbi.nlm.nih.gov/pubmed/31764119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000412
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