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Programmed death-1 restrains the germinal center in type 1 diabetes

Programmed death-1 (PD-1) inhibits T and B cell function upon ligand binding. PD-1 blockade revolutionized cancer treatment, and while numerous patients respond, some develop autoimmune-like symptoms or overt autoimmunity characterized by autoantibody production. PD-1 inhibition accelerates autoimmu...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Martinov, Tijana, Swanson, Linnea A., Breed, Elise R., Tucker, Christopher G., Dwyer, Alexander J., Johnson, Jenna K., Mitchell, Jason S., Sahli, Nathanael L., Wilson, Joseph C., Singh, Lovejot M., Hogquist, Kristin A., Spanier, Justin A., Fife, Brian T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083260/
https://ncbi.nlm.nih.gov/pubmed/31324724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801535
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