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Programmed death-1 restrains the germinal center in type 1 diabetes
Programmed death-1 (PD-1) inhibits T and B cell function upon ligand binding. PD-1 blockade revolutionized cancer treatment, and while numerous patients respond, some develop autoimmune-like symptoms or overt autoimmunity characterized by autoantibody production. PD-1 inhibition accelerates autoimmu...
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| Gepubliceerd in: | J Immunol |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7083260/ https://ncbi.nlm.nih.gov/pubmed/31324724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801535 |
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