Striatal Dopamine D(2)-Muscarinic Acetylcholine M(1) Receptor–Receptor Interaction in a Model of Movement Disorders

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor control deficits, which is associated with the loss of striatal dopaminergic neurons from the substantia nigra. In parallel to dopaminergic denervation, there is an increase of acetylcholine within the striatum, resultin...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Crans, René A. J., Wouters, Elise, Valle-León, Marta, Taura, Jaume, Massari, Caio M., Fernández-Dueñas, Víctor, Stove, Christophe P., Ciruela, Francisco
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083216/
https://ncbi.nlm.nih.gov/pubmed/32231561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00194
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