Striatal Dopamine D(2)-Muscarinic Acetylcholine M(1) Receptor–Receptor Interaction in a Model of Movement Disorders

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor control deficits, which is associated with the loss of striatal dopaminergic neurons from the substantia nigra. In parallel to dopaminergic denervation, there is an increase of acetylcholine within the striatum, resultin...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Crans, René A. J., Wouters, Elise, Valle-León, Marta, Taura, Jaume, Massari, Caio M., Fernández-Dueñas, Víctor, Stove, Christophe P., Ciruela, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083216/
https://ncbi.nlm.nih.gov/pubmed/32231561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00194
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