Compassionate Use of the ROCK Inhibitor Fasudil in Three Patients With Amyotrophic Lateral Sclerosis

The Rho kinase (ROCK) inhibitor Fasudil is a promising drug for a disease-modifying therapy of amyotrophic lateral sclerosis (ALS). In preclinical models, Fasudil was shown to increase motor neuron survival, inhibit axonal degeneration, enhance axonal regeneration and modulate microglial function in...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Front Neurol
Main Authors: Koch, Jan C., Kuttler, Josua, Maass, Fabian, Lengenfeld, Teresa, Zielke, Eirini, Bähr, Mathias, Lingor, Paul
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Neurology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083210/
https://ncbi.nlm.nih.gov/pubmed/32231638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.00173
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares