Compassionate Use of the ROCK Inhibitor Fasudil in Three Patients With Amyotrophic Lateral Sclerosis

The Rho kinase (ROCK) inhibitor Fasudil is a promising drug for a disease-modifying therapy of amyotrophic lateral sclerosis (ALS). In preclinical models, Fasudil was shown to increase motor neuron survival, inhibit axonal degeneration, enhance axonal regeneration and modulate microglial function in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Neurol
Päätekijät: Koch, Jan C., Kuttler, Josua, Maass, Fabian, Lengenfeld, Teresa, Zielke, Eirini, Bähr, Mathias, Lingor, Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2020
Aiheet:
Neurology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083210/
https://ncbi.nlm.nih.gov/pubmed/32231638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.00173
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia