Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells

MicroRNAs (miRs) are one of the most important post-transcriptional repressors of gene expression. However, miR-574-5p has recently been shown to positively regulate the expression of microsomal prostaglandin E-synthase-1 (mPGES-1), a key enzyme in the prostaglandin E(2) (PGE(2)) biosynthesis, by ac...

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Vydáno v:Front Pharmacol
Hlavní autoři: Emmerich, Anne C., Wellstein, Julia, Ossipova, Elena, Baumann, Isabell, Lengqvist, Johan, Kultima, Kim, Jakobsson, Per-Johan, Steinhilber, Dieter, Saul, Meike J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082395/
https://ncbi.nlm.nih.gov/pubmed/32231562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00196
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