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Elongin C Contributes to RNA Polymerase II Degradation by the Interferon Antagonist NSs of La Crosse Orthobunyavirus

Mosquito-borne La Crosse virus (LACV; genus Orthobunyavirus, family Peribunyaviridae, order Bunyavirales) causes up to 100 annual cases of severe meningoencephalitis in children and young adults in the United States. A major virulence factor of LACV is the nonstructural protein NSs, which inhibits h...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Schoen, Andreas, Lau, Simone, Verbruggen, Paul, Weber, Friedemann
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081911/
https://ncbi.nlm.nih.gov/pubmed/31941775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02134-19
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