Discovery and Selection of Hepatitis B Virus-Derived T Cell Epitopes for Global Immunotherapy Based on Viral Indispensability, Conservation, and HLA-Binding Strength

Immunotherapy represents an attractive option for the treatment of chronic hepatitis B virus (HBV) infection. The HBV proteins polymerase (Pol) and HBx are of special interest for antigen-specific immunotherapy because they are essential for viral replication and have been associated with viral cont...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: de Beijer, Monique T. A., Jansen, Diahann T. S. L., Dou, Yingying, van Esch, Wim J. E., Mok, Juk Yee, Maas, Mariëlle J. P., Brasser, Giso, de Man, Robert A., Woltman, Andrea M., Buschow, Sonja I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081907/
https://ncbi.nlm.nih.gov/pubmed/31852786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01663-19
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