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Human Epitopes Identified from Herpes Simplex Virus Tegument Protein VP11/12 (UL46) Recall Multifunctional Effector Memory CD4(+) T(EM) Cells in Asymptomatic Individuals and Protect from Ocular Herpes Infection and Disease in “Humanized” HLA-DR Transgenic Mice
While the role of CD8(+) T cells in the control of herpes simplex virus 1 (HSV-1) infection and disease is gaining wider acceptance, a direct involvement of effector CD4(+) T cells in this protection and the phenotype and function of HSV-specific human CD4(+) T cell epitopes remain to be fully eluci...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7081904/ https://ncbi.nlm.nih.gov/pubmed/31915285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01991-19 |
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