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Sensitivity of Alphaviruses to G3BP Deletion Correlates with Efficiency of Replicase Polyprotein Processing

We present a comprehensive overview of the dependency of several Old World alphaviruses for the host protein G3BP. Based on their replication ability in G3BP-deleted cells, Old World alphaviruses can be categorized into two groups, being either resistant or sensitive to G3BP deletion. We observed th...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Götte, Benjamin, Utt, Age, Fragkoudis, Rennos, Merits, Andres, McInerney, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081891/
https://ncbi.nlm.nih.gov/pubmed/31941782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01681-19
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