Cathepsin K regulates localization and secretion of Tartrate-Resistant Acid Phosphatase (TRAP) in TRAP-overexpressing MDA-MB-231 breast cancer cells

BACKGROUND: Tartrate–resistant acid phosphatase (TRAP/ ACP5) belongs to the binuclear metallophosphatase family and is present in two isoforms. The primary translation product is an uncleaved TRAP 5a isoform with low phosphatase activity. TRAP 5a can be post-translationally processed to a cleaved TR...

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Bibliografski detalji
Izdano u:BMC Mol Cell Biol
Glavni autori: Reithmeier, Anja, Norgård, Maria, Ek-Rylander, Barbro, Näreoja, Tuomas, Andersson, Göran
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081696/
https://ncbi.nlm.nih.gov/pubmed/32188406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00253-6
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