Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes metastasis-related properties via TGFβ2/TβR and CD44 in MDA-MB-231 breast cancer cells

BACKGROUND: Tartrate-resistant acid phosphatase (TRAP/ACP5), a metalloenzyme that is characteristic for its expression in activated osteoclasts and in macrophages, has recently gained considerable focus as a driver of metastasis and was associated with clinically relevant parameters of cancer progre...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Reithmeier, Anja, Panizza, Elena, Krumpel, Michael, Orre, Lukas M., Branca, Rui M. M., Lehtiö, Janne, Ek-Rylander, Barbro, Andersson, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602878/
https://ncbi.nlm.nih.gov/pubmed/28915803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3616-7
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