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A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages

The enzyme tartrate resistant acid phosphatase (TRAP, two isoforms 5a and 5b) is highly expressed in alveolar macrophages, but its function there is unclear and potent selective inhibitors of TRAP are required to assess functional aspects of the protein. We found higher TRAP activity/expression in l...

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書誌詳細
出版年:Sci Rep
主要な著者: Boorsma, Carian E., van der Veen, T. Anienke, Putri, Kurnia S. S., de Almeida, Andreia, Draijer, Christina, Mauad, Thais, Fejer, Gyorgy, Brandsma, Corry-Anke, van den Berge, Maarten, Bossé, Yohan, Sin, Don, Hao, Ke, Reithmeier, Anja, Andersson, Göran, Olinga, Peter, Timens, Wim, Casini, Angela, Melgert, Barbro N.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626781/
https://ncbi.nlm.nih.gov/pubmed/28974738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12623-w
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