A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages

The enzyme tartrate resistant acid phosphatase (TRAP, two isoforms 5a and 5b) is highly expressed in alveolar macrophages, but its function there is unclear and potent selective inhibitors of TRAP are required to assess functional aspects of the protein. We found higher TRAP activity/expression in l...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Boorsma, Carian E., van der Veen, T. Anienke, Putri, Kurnia S. S., de Almeida, Andreia, Draijer, Christina, Mauad, Thais, Fejer, Gyorgy, Brandsma, Corry-Anke, van den Berge, Maarten, Bossé, Yohan, Sin, Don, Hao, Ke, Reithmeier, Anja, Andersson, Göran, Olinga, Peter, Timens, Wim, Casini, Angela, Melgert, Barbro N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626781/
https://ncbi.nlm.nih.gov/pubmed/28974738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12623-w
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