Induced DNA hypomethylation by Folic Acid Deprivation in Bovine Fibroblast Donor Cells Improves Reprogramming of Somatic Cell Nuclear Transfer Embryos

Aberrant patterns of DNA methylation are consistent events in SCNT derived embryos and mechanistically are believed to be related to abnormal development. While some epigenetic drugs have been used in attempts to improve SCNT efficiency but some concerns remained toward the safety of these drugs on...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Jozi, Mina, Jafarpour, Farnoosh, Moradi, Reza, Zadegan, Faezeh Ghazvini, Karbalaie, Khadijeh, Nasr-Esfahani, Mohammad Hossein
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081283/
https://ncbi.nlm.nih.gov/pubmed/32193457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61797-3
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