Somatic Cell-Induced Hyperacetylation, But Not Hypomethylation, Positively and Reversibly Affects the Efficiency of In Vitro Cloned Blastocyst Production in Cattle

5-Aza-2′-deoxycytidine (AzC), trichostatin A (TSA), and its natural mimetic, sodium butyrate (NaB), are antineoplastic drugs that can modify the epigenetic status of donor cells prior to somatic cell nuclear transfer (SCNT). In this study, we used fibroblast cells treated with these drugs to investi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Jafarpour, Farnoosh, Hosseini, Sayed Morteza, Hajian, Mehdi, Forouzanfar, Mohsen, Ostadhosseini, Somayyeh, Abedi, Parvaneh, Gholami, Soghra, Ghaedi, Kamran, Gourabi, Hamid, Shahverdi, Abdol Hossein, Vosough, Ahmad Dizaj Taghi, Nasr-Esfahani, Mohammad Hossein
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2011
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229819/
https://ncbi.nlm.nih.gov/pubmed/21919704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2011.0005
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge