Human Pluripotent Stem Cell-Derived Hepatocytes Show Higher Transcriptional Correlation with Adult Liver Tissue than with Fetal Liver Tissue

[Image: see text] Human pluripotent stem cell-derived hepatocytes (hPSC-HEP) display many properties of mature hepatocytes, including expression of important genes of the drug metabolizing machinery, glycogen storage, and production of multiple serum proteins. To this date, hPSC-HEP do not, however,...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Ghosheh, Nidal, Küppers-Munther, Barbara, Asplund, Annika, Andersson, Christian X., Björquist, Petter, Andersson, Tommy B., Carén, Helena, Simonsson, Stina, Sartipy, Peter, Synnergren, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081255/
https://ncbi.nlm.nih.gov/pubmed/32201767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03514
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