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Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases

There is a strong anticipated future for human induced pluripotent stem cell-derived hepatocytes (hiPS-HEP), but so far, their use has been limited due to insufficient functionality. We investigated the potential of hiPS-HEP as an in vitro model for metabolic diseases by combining transcriptomics wi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Holmgren, Gustav, Ulfenborg, Benjamin, Asplund, Annika, Toet, Karin, Andersson, Christian X, Hammarstedt, Ann, Hanemaaijer, Roeland, Küppers-Munther, Barbara, Synnergren, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014160/
https://ncbi.nlm.nih.gov/pubmed/31940797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020469
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