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Identification of novel biomarkers for doxorubicin-induced toxicity in human cardiomyocytes derived from pluripotent stem cells

Doxorubicin is a chemotherapeutic agent indicated for the treatment of a variety of cancer types, including leukaemia, lymphomas, and many solid tumours. The use of doxorubicin is, however, associated with severe cardiotoxicity, often resulting in early discontinuation of the treatment. Importantly,...

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Bibliografische gegevens
Gepubliceerd in:Toxicology
Hoofdauteurs: Holmgren, Gustav, Synnergren, Jane, Bogestål, Yalda, Améen, Caroline, Åkesson, Karolina, Holmgren, Sandra, Lindahl, Anders, Sartipy, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326176/
https://ncbi.nlm.nih.gov/pubmed/25529476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2014.12.018
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