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Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver

Estrogen sulfotransferase (SULT1E1) inactivates estrogen and regulates its metabolic homeostats. Whereas SULT1E1 is expressed low in the liver of adult mice, it is induced by phenobarbital (PB) treatment or spontaneously in diabetic livers via nuclear receptors. Utilizing constitutive active/androst...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Yi, MyeongJin, Fashe, Muluneh, Arakawa, Shingo, Moore, Rick, Sueyoshi, Tatsuya, Negishi, Masahiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081254/
https://ncbi.nlm.nih.gov/pubmed/32193417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61767-9
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