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Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver

Estrogen sulfotransferase (SULT1E1) inactivates estrogen and regulates its metabolic homeostats. Whereas SULT1E1 is expressed low in the liver of adult mice, it is induced by phenobarbital (PB) treatment or spontaneously in diabetic livers via nuclear receptors. Utilizing constitutive active/androst...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Yi, MyeongJin, Fashe, Muluneh, Arakawa, Shingo, Moore, Rick, Sueyoshi, Tatsuya, Negishi, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081254/
https://ncbi.nlm.nih.gov/pubmed/32193417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61767-9
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