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Somatic Mutations in HER2 and Implications for Current Treatment Paradigms in HER2-Positive Breast Cancer

In one of every four or five cases of breast cancer, the human epidermal growth factor receptor-2 (HER2) gene is overexpressed. These carcinomas are known as HER2-positive. HER2 overexpression is linked to an aggressive phenotype and a lower rate of disease-free and overall survival. Drugs such as t...

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Dades bibliogràfiques
Publicat a:J Oncol
Autors principals: Gaibar, Maria, Beltrán, Laura, Romero-Lorca, Alicia, Fernández-Santander, Ana, Novillo, Apolonia
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081042/
https://ncbi.nlm.nih.gov/pubmed/32256585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6375956
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