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Genetic Variants of ANGPT1, CD39, FGF2 and MMP9 Linked to Clinical Outcome of Bevacizumab Plus Chemotherapy for Metastatic Colorectal Cancer

Angiogenesis pathway genes show substantial genetic variability causing inter-individual differences in responses to anti-angiogenic drugs. We examined 20 single nucleotide polymorphisms (SNPs) in 13 of these genes to predict tumour response and clinical outcome measured as progression free survival...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gaibar, María, Galán, Miguel, Romero-Lorca, Alicia, Antón, Beatriz, Malón, Diego, Moreno, Amalia, Fernández-Santander, Ana, Novillo, Apolonia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866547/
https://ncbi.nlm.nih.gov/pubmed/33573134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031381
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