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Relationship between Genotypes Sult1a2 and Cyp2d6 and Tamoxifen Metabolism in Breast Cancer Patients

Tamoxifen is a pro-drug widely used in breast cancer patients to prevent tumor recurrence. Prior work has revealed a role of cytochrome and sulfotransferase enzymes in tamoxifen metabolism. In this descriptive study, correlations were examined between concentrations of tamoxifen metabolites and geno...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fernández-Santander, Ana, Gaibar, María, Novillo, Apolonia, Romero-Lorca, Alicia, Rubio, Margarita, Chicharro, Luis Miguel, Tejerina, Armando, Bandrés, Fernando
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726442/
https://ncbi.nlm.nih.gov/pubmed/23922954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070183
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