Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Transients

Although biomimetic stimuli, such as microgroove-induced alignment (μ), triiodothyronine (T3) induction, and electrical conditioning (EC), have been reported to promote maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), a systematic examination of their combinatorial effect...

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Dades bibliogràfiques
Publicat a:Front Physiol
Autors principals: Wong, Andy On-Tik, Wong, Nicodemus, Geng, Lin, Chow, Maggie Zi-ying, Lee, Eugene K., Wu, Hongkai, Khine, Michelle, Kong, Chi-Wing, Costa, Kevin D., Keung, Wendy, Cheung, Yiu-Fai, Li, Ronald A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080659/
https://ncbi.nlm.nih.gov/pubmed/32226389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00165
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