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Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome

Living cells regulate key cellular processes by spatial organisation of catalytically active proteins in higher-order signalling complexes. These act as organising centres to facilitate proximity-induced activation and inhibition of multiple intrinsically weakly associating signalling components, wh...

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Bibliografski detalji
Izdano u:Nat Catal
Glavni autori: Rosier, Bas J.H.M., Markvoort, Albert J., Gumí Audenis, Berta, Roodhuizen, Job A.L., den Hamer, Anniek, Brunsveld, Luc, de Greef, Tom F.A.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080557/
https://ncbi.nlm.nih.gov/pubmed/32190819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41929-019-0403-7
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