Counterion-Dependent Mechanisms of DNA Origami Nanostructure Stabilization Revealed by Atomistic Molecular Simulation

[Image: see text] The DNA origami technique has proven to have tremendous potential for therapeutic and diagnostic applications like drug delivery, but the relatively low concentrations of cations in physiological fluids cause destabilization and degradation of DNA origami constructs preventing in v...

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Publicat a:ACS Nano
Autors principals: Roodhuizen, Job A. L., Hendrikx, Philip J. T. M., Hilbers, Peter A. J., de Greef, Tom F. A., Markvoort, Albert J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764110/
https://ncbi.nlm.nih.gov/pubmed/31502824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b05650
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