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Metabolomics analysis reveals perturbations of cerebrocortical metabolic pathways in the Pah(enu2) mouse model of phenylketonuria
AIMS: Phenylketonuria (PKU), which is caused by mutations in the phenylalanine hydroxylase (PAH) gene, is one of the most common inherited diseases of amino acid metabolism. Phenylketonuria is characterized by an abnormal accumulation of phenylalanine and its metabolites in body fluids and brain tis...
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| Publicado no: | CNS Neurosci Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7080435/ https://ncbi.nlm.nih.gov/pubmed/31471952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13214 |
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