Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long-Lived Growth Hormone Receptor Null Mice

Despite increased longevity and resistance to multiple stressors, growth hormone receptor null (GHRKO) mice exhibit severe skeletal impairment. The role of GHR in maintaining osteocyte mitochondrial function is unknown. We found that GHR ablation was detrimental to osteocyte mitochondrial function....

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Detaylı Bibliyografya
Yayımlandı:J Bone Miner Res
Asıl Yazarlar: Liu, Zhongbo, Solesio, Maria E, Schaffler, Mitchell B, Frikha-Benayed, Dorra, Rosen, Clifford J, Werner, Haim, Kopchick, John J, Pavlov, Evgeny V, Abramov, Andrey Y, Yakar, Shoshana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080402/
https://ncbi.nlm.nih.gov/pubmed/30216544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3573
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