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DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH
Bone minerals are acquired during growth and are key determinants of adult skeletal health. During puberty, the serum levels of growth hormone (GH) and its downstream effector IGF-1 increase and play critical roles in bone acquisition. The goal of the current study was to determine how bone cells in...
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| Опубликовано в: : | FASEB J |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Federation of American Societies for Experimental Biology
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714547/ https://ncbi.nlm.nih.gov/pubmed/26481310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275859 |
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