DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH

Bone minerals are acquired during growth and are key determinants of adult skeletal health. During puberty, the serum levels of growth hormone (GH) and its downstream effector IGF-1 increase and play critical roles in bone acquisition. The goal of the current study was to determine how bone cells in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:FASEB J
Päätekijät: Liu, Zhongbo, Kennedy, Oran D., Cardoso, Luis, Basta-Pljakic, Jelena, Partridge, Nicola C., Schaffler, Mitchell B., Rosen, Clifford J., Yakar, Shoshana
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Federation of American Societies for Experimental Biology 2016
Aiheet:
Research Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714547/
https://ncbi.nlm.nih.gov/pubmed/26481310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275859
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