DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH

Bone minerals are acquired during growth and are key determinants of adult skeletal health. During puberty, the serum levels of growth hormone (GH) and its downstream effector IGF-1 increase and play critical roles in bone acquisition. The goal of the current study was to determine how bone cells in...

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發表在:FASEB J
Main Authors: Liu, Zhongbo, Kennedy, Oran D., Cardoso, Luis, Basta-Pljakic, Jelena, Partridge, Nicola C., Schaffler, Mitchell B., Rosen, Clifford J., Yakar, Shoshana
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2016
主題:
Research Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714547/
https://ncbi.nlm.nih.gov/pubmed/26481310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275859
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