Biological activity of weekly ONC201 in adult recurrent glioblastoma patients

BACKGROUND: ONC201 is a dopamine receptor D2 (DRD2) antagonist that penetrates the blood–brain barrier. ONC201 efficacy has been shown in glioblastoma animal models and is inversely correlated with dopamine receptor DRD5 expression. ONC201 is well tolerated in adult recurrent glioblastoma patients w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Arrillaga-Romany, Isabel, Odia, Yazmin, Prabhu, Varun V, Tarapore, Rohinton S, Merdinger, Krystal, Stogniew, Martin, Oster, Wolfgang, Allen, Joshua E, Mehta, Minesh, Batchelor, Tracy T, Wen, Patrick Y
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Clinical Investigations
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080220/
https://ncbi.nlm.nih.gov/pubmed/31702782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz164
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