Biological activity of weekly ONC201 in adult recurrent glioblastoma patients

BACKGROUND: ONC201 is a dopamine receptor D2 (DRD2) antagonist that penetrates the blood–brain barrier. ONC201 efficacy has been shown in glioblastoma animal models and is inversely correlated with dopamine receptor DRD5 expression. ONC201 is well tolerated in adult recurrent glioblastoma patients w...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Arrillaga-Romany, Isabel, Odia, Yazmin, Prabhu, Varun V, Tarapore, Rohinton S, Merdinger, Krystal, Stogniew, Martin, Oster, Wolfgang, Allen, Joshua E, Mehta, Minesh, Batchelor, Tracy T, Wen, Patrick Y
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Clinical Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080220/
https://ncbi.nlm.nih.gov/pubmed/31702782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz164
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki