Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo

Avian coronavirus infectious bronchitis virus (IBV) infects domestic fowl, resulting in respiratory disease and causing serious losses in unprotected birds. Its control is mainly achieved by using live attenuated vaccines. Here we explored the possibilities for rationally attenuating IBV to improve...

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Detaylı Bibliyografya
Yayımlandı:J Gen Virol
Asıl Yazarlar: Laconi, Andrea, van Beurden, Steven J., Berends, Alinda J., Krämer-Kühl, Annika, Jansen, Christine A., Spekreijse, Dieuwertje, Chénard, Gilles, Philipp, Hans-Christian, Mundt, Egbert, Rottier, Peter J. M., Hélène Verheije, M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Microbiology Society 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079694/
https://ncbi.nlm.nih.gov/pubmed/30067172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001130
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