Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo

Avian coronavirus infectious bronchitis virus (IBV) infects domestic fowl, resulting in respiratory disease and causing serious losses in unprotected birds. Its control is mainly achieved by using live attenuated vaccines. Here we explored the possibilities for rationally attenuating IBV to improve...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Gen Virol
Päätekijät: Laconi, Andrea, van Beurden, Steven J., Berends, Alinda J., Krämer-Kühl, Annika, Jansen, Christine A., Spekreijse, Dieuwertje, Chénard, Gilles, Philipp, Hans-Christian, Mundt, Egbert, Rottier, Peter J. M., Hélène Verheije, M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Microbiology Society 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079694/
https://ncbi.nlm.nih.gov/pubmed/30067172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001130
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