ILK supports RhoA/ROCK-mediated contractility of human intestinal epithelial crypt cells by inducing the fibrillogenesis of endogenous soluble fibronectin during the spreading process

BACKGROUND: Fibronectin (FN) assembly into an insoluble fibrillar matrix is a crucial step in many cell responses to extracellular matrix (ECM) properties, especially with regards to the integrin-related mechanosensitive signaling pathway. We have previously reported that the silencing of expression...

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Bibliografiske detaljer
Udgivet i:BMC Mol Cell Biol
Main Authors: Gagné, David, Benoit, Yannick D., Groulx, Jean-François, Vachon, Pierre H., Beaulieu, Jean-François
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079544/
https://ncbi.nlm.nih.gov/pubmed/32183701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00259-0
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