Integrin α8β1 regulates adhesion, migration and proliferation of human intestinal crypt cells via a predominant RhoA/ROCK-dependent mechanism

Background. Integrins are transmembrane αβ heterodimer receptors that function as structural and functional bridges between the cytoskeleton and ECM (extracellular matrix) molecules. The RGD (arginine-glycine-aspartate tripeptide motif)-dependent integrin α8β1 has been shown to be involved in variou...

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Detalhes bibliográficos
Main Authors: Benoit, Yannick D., Lussier, Carine, Ducharme, Pierre-Alexandre, Sivret, Sophie, Schnapp, Lynn M., Basora, Nuria, Beaulieu, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782361/
https://ncbi.nlm.nih.gov/pubmed/19527220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BC20090060
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