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Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification

BACKGROUND: Cerebrospinal fluid biomarker profiles characterized by decreased amyloid-beta peptide levels and increased total and phosphorylated tau levels at threonine 181 (pT181) are currently used to discriminate between Alzheimer’s disease and other neurodegenerative diseases. However, these cha...

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Bibliographische Detailangaben
Veröffentlicht in:Alzheimers Res Ther
Hauptverfasser: Barthélemy, Nicolas R., Bateman, Randall J., Hirtz, Christophe, Marin, Philippe, Becher, François, Sato, Chihiro, Gabelle, Audrey, Lehmann, Sylvain
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079453/
https://ncbi.nlm.nih.gov/pubmed/32183883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00596-4
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