Plasma phospho-tau181 increases with Alzheimer’s disease clinical severity and is associated with tau-PET and amyloid-PET

INTRODUCTION: We examined and compared plasma phospho-tau181 (pTau181) and total tau: 1) across the Alzheimer’s disease (AD) clinical spectrum; 2) in relation to brain amyloid (Aβ) PET, tau PET, and cortical thickness; and 3) as a screening tool for elevated brain Aβ. METHODS: Participants included...

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書誌詳細
出版年:Alzheimers Dement
主要な著者: Mielke, Michelle M., Hagen, Clinton E., Xu, Jing, Chai, Xiyun, Vemuri, Prashanthi, Lowe, Val J., Airey, David C., Knopman, David S., Roberts, Rosebud O., Machulda, Mary M., Jack, Clifford R., Petersen, Ronald C., Dage, Jeffrey L.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097897/
https://ncbi.nlm.nih.gov/pubmed/29626426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.02.013
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