Supramolecular clustering of the cardiac sodium channel Nav1.5 in HEK293F cells, with and without the auxiliary β3‐subunit

Voltage‐gated sodium channels comprise an ion‐selective α‐subunit and one or more associated β‐subunits. The β3‐subunit (encoded by the SCN3B gene) is an important physiological regulator of the heart‐specific sodium channel, Nav1.5. We have previously shown that when expressed alone in HEK293F cell...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Salvage, Samantha C., Rees, Johanna S., McStea, Alexandra, Hirsch, Michael, Wang, Lin, Tynan, Christopher J., Reed, Matthew W., Irons, Jennifer R., Butler, Richard, Thompson, Andrew J., Martin-Fernandez, Marisa L., Huang, Christopher L.‐H., Jackson, Antony P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079131/
https://ncbi.nlm.nih.gov/pubmed/31950564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201701473RR
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