A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line

Among the nine voltage-gated sodium channel (NaV) subtypes, NaV1.8 is an attractive therapeutic target for pain. The heterologous expression of recombinant NaV1.8 currents is of particular importance for its electrophysiological and pharmacological studies. However, NaV1.8 expresses no or low-level...

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Vydáno v:Front Pharmacol
Hlavní autoři: Zhou, Xi, Zhang, Yunxiao, Tang, Dongfang, Liang, Songping, Chen, Ping, Tang, Cheng, Liu, Zhonghua
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900924/
https://ncbi.nlm.nih.gov/pubmed/29686617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00337
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