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A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line

Among the nine voltage-gated sodium channel (NaV) subtypes, NaV1.8 is an attractive therapeutic target for pain. The heterologous expression of recombinant NaV1.8 currents is of particular importance for its electrophysiological and pharmacological studies. However, NaV1.8 expresses no or low-level...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Zhou, Xi, Zhang, Yunxiao, Tang, Dongfang, Liang, Songping, Chen, Ping, Tang, Cheng, Liu, Zhonghua
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900924/
https://ncbi.nlm.nih.gov/pubmed/29686617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00337
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