A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line

Among the nine voltage-gated sodium channel (NaV) subtypes, NaV1.8 is an attractive therapeutic target for pain. The heterologous expression of recombinant NaV1.8 currents is of particular importance for its electrophysiological and pharmacological studies. However, NaV1.8 expresses no or low-level...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Zhou, Xi, Zhang, Yunxiao, Tang, Dongfang, Liang, Songping, Chen, Ping, Tang, Cheng, Liu, Zhonghua
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900924/
https://ncbi.nlm.nih.gov/pubmed/29686617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00337
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