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Real‐time dissolved carbon dioxide monitoring II: Surface aeration intensification for efficient CO(2) removal in shake flasks and mini‐bioreactors leads to superior growth and recombinant protein yields

Mass transfer is known to play a critical role in bioprocess performance and henceforth monitoring dissolved O(2) (DO) and dissolved CO(2) (dCO(2)) is of paramount importance. At bioreactor level these parameters can be monitored online and can be controlled by sparging air/oxygen or stirrer speed....

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Chopda, Viki R., Holzberg, Timothy, Ge, Xudong, Folio, Brandon, Wong, Lynn, Tolosa, Michael, Kostov, Yordan, Tolosa, Leah, Rao, Govind
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078866/
https://ncbi.nlm.nih.gov/pubmed/31840800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27252
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