Real‐time dissolved carbon dioxide monitoring II: Surface aeration intensification for efficient CO(2) removal in shake flasks and mini‐bioreactors leads to superior growth and recombinant protein yields

Mass transfer is known to play a critical role in bioprocess performance and henceforth monitoring dissolved O(2) (DO) and dissolved CO(2) (dCO(2)) is of paramount importance. At bioreactor level these parameters can be monitored online and can be controlled by sparging air/oxygen or stirrer speed....

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Vydáno v:Biotechnol Bioeng
Hlavní autoři: Chopda, Viki R., Holzberg, Timothy, Ge, Xudong, Folio, Brandon, Wong, Lynn, Tolosa, Michael, Kostov, Yordan, Tolosa, Leah, Rao, Govind
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
ARTICLES
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078866/
https://ncbi.nlm.nih.gov/pubmed/31840800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27252
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