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Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection

Human noroviruses (HuNoVs) are the leading cause of nonbacterial gastroenteritis worldwide. Histo-blood group antigen (HBGA) expression is an important susceptibility factor for HuNoV infection based on controlled human infection models and epidemiologic studies that show an association of secretor...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Haga, Kei, Ettayebi, Khalil, Tenge, Victoria R., Karandikar, Umesh C., Lewis, Miranda A., Lin, Shih-Ching, Neill, Frederick H., Ayyar, B. Vijayalakshmi, Zeng, Xi-Lei, Larson, Göran, Ramani, Sasirekha, Atmar, Robert L., Estes, Mary K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078471/
https://ncbi.nlm.nih.gov/pubmed/32184242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00251-20
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