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Replication of Human Noroviruses in Stem Cell-Derived Human Enteroids

The major barrier to research and development of effective interventions for human noroviruses (HuNoVs) has been the lack of a robust and reproducible in vitro cultivation system. HuNoVs are the leading cause of gastroenteritis worldwide. We report successful cultivation of multiple HuNoV strains in...

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Publicado en:Science
Main Authors: Ettayebi, Khalil, Crawford, Sue E., Murakami, Kosuke, Broughman, James R., Karandikar, Umesh, Tenge, Victoria R., Neill, Frederick H., Blutt, Sarah E., Zeng, Xi-Lei, Qu, Lin, Kou, Baijun, Opekun, Antone R., Burrin, Douglas, Graham, David Y., Ramani, Sasirekha, Atmar, Robert L., Estes, Mary K.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305121/
https://ncbi.nlm.nih.gov/pubmed/27562956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf5211
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