Structural Basis of Ca(2+)-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins

The posttranslational Ca(2+)-dependent “clip-and-link” activity of large repeat-in-toxin (RTX) proteins starts by Ca(2+)-dependent structural rearrangement of a highly conserved self-processing module (SPM). Subsequently, an internal aspartate-proline (Asp-Pro) peptide bond at the N-terminal end of...

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Veröffentlicht in:mBio
Hauptverfasser: Kuban, Vojtech, Macek, Pavel, Hritz, Jozef, Nechvatalova, Katerina, Nedbalcova, Katerina, Faldyna, Martin, Sebo, Peter, Zidek, Lukas, Bumba, Ladislav
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078468/
https://ncbi.nlm.nih.gov/pubmed/32184239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00226-20
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